Findings suggest the MoS has potential to be a helpful, objective measurement in a variety of clinically affected populations. This is the first systematic review to assess use of the MoS and the first to consider its clinical application. A variety of centre of mass, base of support and MoS definitions and calculations were described. Most participants were assessed in a gait laboratory using motion capture technology, whilst 2 studies used instrumented shoes. More than 15 different clinical populations were studied, most commonly post-stroke and unilateral transtibial amputee populations. Thirty-one studies were included in the final review. Extracted data were collected per a prospectively defined list, which included: population type, method of data analysis and model building, walking tasks undertaken, and interpretation of the MoS. All articles measured the MoS of a pathologically affected adult human population whilst walking in a straight line. MethodsĪ systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA) in the following databases: Web of Science, PubMed, UCL Library Explore, Cochrane Library, Scopus. The objectives are to describe the types of pathological gait that are assessed using the MoS, to examine the methods used to assess MoS and to examine the way the MoS data is presented and interpreted. Increasingly, researchers are using the MoS to assess the stability of pathological populations to gauge their stability capabilities and coping strategies, or as an objective marker of outcome, response to treatment or disease progression. The Margin of Stability (MoS) is a widely used objective measure of dynamic stability during gait.
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